The antioxidant potentials of both extracts were assessed using l,ldiphenyl2picrylhydrazyl dpph free radical. Phytochemistry and pharmacognosy of the genus psorospermum. Flavonoids were reported to have antioxidative and free radical scavenging. Febrifugum magnum, or, common water the best cure for.
The results showed that psorospermum febrifugum possess good antiinflammatory activity. Psorospermum wikispecies wikispecies, free species. Indigenous traditional knowledge of medicinal plants used by. Citation export bibtex endnote ris cite this paper. Isolation and characterisation of antituberculosis. These plants could be potential rich sources of natural antioxidants and developed into functional food for nutrition and. How to convert pdf to dwf with a free download 5 steps it still works. Aug 29, 2019 journal of applied biosciences issn 1997 5902 volume 9, july 2019 agbogba felicienne, sacramento teniola isabelle, tchogou atchade pascal, medoatinsa esperance, kanfon estelle rose, atakpa eugene, agbangnan dossa c. Isolation and characterisation of antituberculosis compounds. If you would like to participate, visit the project page. Jan 23, 20 the genus psorospermum baker tribe vismieae, family guttiferae, subfamily hypericoideae comprises 55 species, mainly of which are represented by shrubs or small trees typically growing in tropical regions of south america, africa, and madasgascar. Medicinal plants of kakamega forests and their consistency applications doi. This page was last edited on 20 december 2019, at 16.
To browse pdf files, you need adobe acrobat reader. Click get books and find your favorite books in the online library. In this article, we describe the synthesis of the two diastereomers of o 5methyl. For chemotaxonomical discrimination between these easily confused species, the total extractive content of the three wood species was determined using four different organic solvents. The fruit is a small berry some 6mm in diameter and bright red when mature.
The percent inhibitions of carrageenaninduced paw oedema per hour were 43. Pdf antiinflammatory properties of psorospermum febrifugum. Download full magnum book or read online anytime anywhere, available in pdf, epub and kindle. Jan 10, 2020 although herpes zoster was a frequently cited condition by the tmp, the only plant species highly cited for treating it was psorospermum febrifugum. Free downloadable animal health articles and posters to be printed as needed. Msonthi no static citation data no static citation data cite. Our primary objective is to assist and guide final year students with well researched and quality project topics, project works, research guides, and project materials, at a very reduced and affordable price.
It lets you view and print pdf files on a variety of hardware and pdf means portable document format. New xanthones from psorospermum febrifugum journal of. Xanthones and vismiones from psorospermum febrifugum. Psorospermum febrifugum spach, mangifera indica l, and warburgia salutaris.
All i get is a blank dark gray window on the new tab that a. It has a long history for its use in folkloric medicines as a. Dalbergia cultrate, dalbergia latifolia, and dalbergia melanoxylon are precious and valuable traded timber species of the genus dalbergia. This work aimed to evaluate the safety of the ethyl acetate fraction of the aqueous extract of this bark. When im not designing pdf sewing patterns, im out planting indigenous trees in my village community. The stem bark of psorospermum febrifugum was collected in mpigi district, misindye hill in buwungu village buwama sub country in uganda. Results and discussion the cold acetone extract of the rootbark of p. The decoction of psorospermum febrifugum slightly increased the total sleep time induced by diazepam 50 mg kg 1 i. Anticancer and antimicrobial activities of some antioxidantrich cameroonian medicinal plants. Pakistan journal of biological sciences 11, 719 725.
Pollination efficiency of apis mellifera adansonii. Psorospermum febrifugum spach clusiaceae was a tropical plant whose root bark was used to treat anemia. Advertisement based on our internal quality systems, this software could be either potentially malicious or may contain unwanted bundled software. High correlation has been established between antioxidant activity and total phenolic content of psorospermum febrifugum, myrianthus arboreus and ceratotheca sesamoides. Psorospermin, a new antileukemic xanthone from psorospermum febrifugum. The active constituents identified in this plant have the capacity to cause dna damage, and to interact with a cytochrome c viral dna crosslink.
The preliminary phytochemical screening of methanol extracts for stem bark, leaves. Im a portland, oregon native who came to africa as a peace corps volunteer in 1999. It also protected mice against pentylene tetrazol, picrotoxinand strychnineinduced seizures. Journal of chemical and pharmaceutical research, 2020, 127. In this study, the bark of psorospermum febrifugum spach and milicia excelsa welw. As resprout survival is known to be sizedependent gignoux et al. Febrifugum magnum, or, common water the best cure for fevers, and probably for the plague. Psorospermum febrifugum wikispecies, free species directory. Pascal, loko frederic, laleye anatole, ategbo jeanmarc, senou maximin and sezan alphonse. The plant psorospermum febrifugum spach also known with the common name. These plants could be potential rich sources of natural antioxidants and. Psorospermum febrifugum, pentadesma butyracea and ficus asperifolia. Jan 01, 1986 this paper reports on the constituents of the rootbark of psorospermum febrifugum, collected in zaire.
Psorospermum febrifugum spach, anaemia, osmotic resistance. Abstract the compounds isolated from psorospermum febrifugum using column chromatography and identified using physicochemical and spectroscopic data were emodin a, 3geranyloxyemodin b and 2geranylemodin c. This article is part of wikiproject hypericaceae, which aims to improve wikipedia s coverage of the plant family hypericaceae and related topics. Iosr journal of pharmacy and biological sciences iosrjpbs eissn. Stub this article has been rated as stubclass on the projects quality scale. Nov 27, 2017 parasitic nematode infections remain a serious global public health threat to humans and animals.
Antioxidant activity and total phenolic content of nine. In safari, when i click download pdf on somebodys instructable, it first looks like its going to download, but nothing really happens. Control of parasitic nematode diseases has continued to rely on use of anthelmintic drugs as there is presently no effective vaccine for the majority of these. Aug 01, 2015 abstract trees with natural resistance to decay by pests contain extractives, which are candidates for wood preservatives. This study investigated the phytochemical screening of some plant extracts against aflatoxin producing fungi in sesame sesamum indicum. Most of the species of the title genus have been used for centuries in the ethnomedical traditions of indigenous african populations as febrifugal. Trees commonly found in malawi ecofriendly pdf sewing. Febrifugum magnum, or, common water the best cure for fevers. Fourier transform infrared ftir spectroscopy was used to analyze. Bn 2546302 with over 20,000 research material guides.
Psorospermin is a natural product that has been shown to have activity against drugresistant leukemia lines and aidsrelated lymphoma. Psorospermum in world checklist of selected plant families. The aqueous extract of the root bark of psorospermum febrifugum. Plants of this genus are largely used in the african folk medicine as febrifugal, antidote against poison and purgative. In this study, psorospermum febrifugum stem bark was investigated for the antibacterial compounds present in its stem bark. The plant psorospermum febrifugum spach is a specie of flowering plants. Chemistry project topics and materials pdf free download 2021. From psorospermum febrifugum extracts, a series of xanthones were isolated, which are responsible for its antiviral and anticancer activities in leukemia and colon cancer. Chemical composition of volatiles extracted from indigenous. A catalyst free 1,3dipolar cycloaddition of c,ncyclic azomethine. The file format was created to improve the efficiency, distribution and communication of rich design data for users of print design files. Molecules free fulltext antimalarial and cytotoxic. Pdf anticancer and antimicrobial activities of some.
Compound 1 was characterized based on spectroscopic and chemical. Psorospermin is a natural product isolated from the roots and stembark of the african plant psorospermum febrifugum 1, 2. Us6683193b2 us10105,964 us10596402a us6683193b2 us 6683193 b2 us6683193 b2 us 6683193b2 us 10596402 a us10596402 a us 10596402a us 6683193 b2 us6683193 b2 us 6683193b2 authority us united states prior art keywords artemether artemisinin acid catalyst reaction mixture. We have psorospermum febrifugum 2633 359 1612 1280 previously shown that treatment of natural extracts with a strong 2geranylemodin 2984 792. Pdf psorospermum febrifugum spach is used in traditional medicine in cameroon to treat epilepsy. Brine shrimp toxicity of some plants used as traditional medicines in. Journal of applied biosciences issn 1997 5902 volume 9, july 2019 agbogba felicienne, sacramento teniola isabelle, tchogou atchade pascal, medoatinsa esperance, kanfon estelle rose, atakpa eugene, agbangnan dossa c. The phytochemical and antioxidant activity of the ethanolic extracts of stem bark of psorospermum febrifugum and harungana madagascariensis were carried out to assess the potential of these extracts as antioxidant agents. It grows in open woodland over a wide range of altitudes. Since a couple days i cannot download pdfs anymore. The first chiral synthesis of the natural product has been reported recently. Html5 allows you to force the visitors web browser to download files, such as. Antipsoriatic and immunomodulatory evaluation of psorospermum.
The ethyl acetate fraction of the extract was administered to wistar rats in a single dose of 2000 mg kg body. Prenylated bianthrones and vismionef from psorospermum febrifugum by b. Another impressive natural xanthone analogue is psorospermin, an ingredient of the african plant psorospermum febrifugum. This activitydirected fractionation led to the isolation of 6geranyloxy3methyl1,8dihydroxyanthrone 1. The genus psorospermum baker tribe vismieae, family guttiferae, subfamily hypericoideae comprises 55 species, mainly of which are represented by shrubs or small trees typically growing in tropical regions of south america, africa, and madasgascar. Low this article has been rated as lowimportance on the projects importance scale. H e a l t h a n d wealth f r o m m e d i c i n a l. Prevalence and factors associated with use of herbal. These metrics are regularly updated to reflect usage leading up to the last few days. These phytochemicals possess antioxidative and free radical scavenging.
Psorospermum febrifugum, the trunk and root bark of which has gained a reputation for effectiveness in treating skin infections and. We cannot guarantee that magnum book is in the library. Pdf psorospermum febrifugum spach hypericaceae decoction. Our primary objective is to assist and guide final year students with well researched and quality project topics, project works, research guides, and project materials, at a very reduced and affordable pr. Antimicrobial prenylated xanthones and anthraquinones from. Acetylvismione d from psorospermum febrifugum sciencedirect. The plants are prosopis africana, psorospermum febrifugum and rhizome of curcuma longa. Recent cancer drug development with xanthone structures na. Ethyl acetate fraction of psorospermum febrifugum extract did.
Modern research has shown the presence of various medically active compounds, but has failed to find any action against malaria. Psorospermum febrifugum in the germplasm resources information network. From censuses to encounter histories encounter histories were generated from individual census data table 1. A systematic fractionation of the root extract ofpsorospermum febrifugum was carried out in an attempt to reisolate the antitumor xanthone psorospermin and related compounds for further structural work and testing. Distortionless enhancement by polarization transfer. Recent cancer drug development with xanthone structures. Psorospermum febrifugum is a flowering plant species in the genus psorospermum occurring in zimbabwe and mozambique. The chemical analysis of the extracts was performed by gas chromatographymass.
Isolation and characterisation of antituberculosis compounds from the leaves of clerodendrum capitatum wild, heeria insignis del and stem bark of psorospermum senegalense spach with abstract, chapters 15, references, and questionnaire. The preliminary phytochemical screening of methanol extracts for stem bark, leaves and rhizome of curcuma longa revealed the presence of saponins, flavonoids, steroids. Psorospermum febrifugum is a flowering plant and belong to the family hypericaceae and found in the tropical areas of the world such as africa, south america and madagascar. Determination of the importance of the stereochemistry of. Pdf asogwa et al antiinflammatory properties of psorospermum. Potential new drug targets and therapeutic approaches for. Psorospermum febrifugum spach family guttiferae on jstor. The rats were then fed either with psorospermum febrifugum spach root. Psorospermin has been shown to intercalate into the dna helix and covalently modify guanine at the n7 position in the major groove through an epoxidemediated electrophilic attack. Psorospermum febrifugum is widely used in traditional medicine in africa, being employed in the treatment of a wide range of conditions but especially those related to fevers and skin problems. Discover how you can force your visitors web browser to download pdf files instead of opening them in the browser.
The board of trustees of the royal botanic gardens, kew. Indigenous traditional knowledge of medicinal plants used. Plants from disturbed savannah vegetation and their usage. Hereswe offer a best and easiest way for every entrepreneur to. Six compounds were found to exhibit significant in vitro cytotoxic activity. Screening and phytochemical analysis of some plants. Anticancer and antimicrobial activities of some antioxidant. We have psorospermum febrifugum 2633 359 1612 1280 previously shown that treatment of natural extracts with a strong 2geranylemodin 2984 792 1150 1098 hydroxide solution leads to informative epr signals which. Susanna bonnet of the university of free state for availing me with. They are also used as a remedy for the treatment of leprosy, skin diseases such as dermatitis, scabies and eczemas and subcutaneous wounds. Biomedresearchinternational 3 trial study of irofulven and gemcitabine in the patients with advanced solid tumor was underway 50. Ethyl acetate fraction of psorospermum febrifugum extract.
Because of the superb nci 60 panel screening test results, psorospermin advanced to clinical trials but further development. H e a l t h a n d wealth f r o m m e d i c i n a l aromatic p. One new prenylated xanthone derivative, named adamaxanthone 1 and one new prenylated anthraquinone derivative, adamaquinone 2 were isolated, respectively, from the methanol extract of the fruits and the stem bark of psorospermum adamauense along with nine known compounds, including two xanthones 1,4,5,7tetrahydroxyxanthone 3 and 1,2,3trimethoxyxanthone 4, two. Were terribly sorry about this and were doing our best to fix it. Short for application, apps let you do everything from listening to music to syncing your phone to you. The inconspicuous flowers are fragrant, creamywhite and some 8mm in diameter. Instructables is experiencing technical difficulties. Article views are the countercompliant sum of full text article downloads since november 2008 both pdf and html across all institutions and individuals. Febrifugum magnum, or, common water the best cure for fevers, and probably for the plague by hancocke, john, 1728. Wikiproject hypericaceae plants rated stubclass, lowimportance this article is part of. The ficus asperifolia and psorospermum febrifugum extracts are selective against a2780cis ovary cells, a cell line which is resistant to the standard anticancer drug cisplatin. Us6683193b2 single pot conversion of artemisinin into.
Before sharing sensitive information, make sure youre on a federal government. It has a long history for its use in folkloric medicines as a remedy for leprosy, epilepsy, insomnia. Plants of agricultural importance included those used for fodder, fattening of livestock and stimulation of milk production. Psorospermum febrifugum spach hypericaceae decoction. Screening and phytochemical analysis of some plants extracts. Psorospermum febrifugum spach is a flowering plant belonging to the family hypericaceae. Natural products as a source of potential cancer chemotherapeutic and chemopreventive agents. These infections cause debilitating conditions in humans and significant economic losses through infection of livestock and crop damage.
Journal of chemical and pharmaceutical research, 2020, 12. Psorospermin, a new antileukemic xanthone from psorospermum. It has also been shown to alkylate dna through an epoxidemediated electrophilic attack, and this alkylation is greatly enhanced at specific sites by topoisomerase ii. If you have a new phone, tablet or computer, youre probably looking to download some new apps to make the most of your new technology. Pdf antipsoriatic and immunomodulatory evaluation of. Various parts of the plants were dried, grounded and extracted in methanolic solvent. Pdf antitumour and cytotoxic xanthones of psorospermum. Create free account to access unlimited books, fast download and ads free. Psorospermum febrifugum spach is used in traditional medicine in cameroon to treat epilepsy. Results over two hundred and fifty plant species of economic importance, belonging to 71 families and 90 genera were reported for their medicinal uses.
I paid for a pro membership specifically to enable this feature. Activitydirected fractionation of the ethanolic extract of psorospermum febrifugum has led to the isolation and structural elucidation of eight new dihydrofuranoxanthones. The aqueous extract of the root bark of psorospermum febrifugum spach. Chemistry project topics and materials pdf free download. In order to select the most promising project, the entrepreneur needs to generate a few ideas about the possible projects. Ng is an academic website built in nigeria that is registered with the corporate affairs commission cac. Although herpes zoster was a frequently cited condition by the tmp, the only plant species highly cited for treating it was psorospermum febrifugum. Crude extracts of daniellia oliveri and psorospermum febrifugum at the 54th annual meeting of the society of toxicology sot, held in san diego, california march 2226, 2015.
1622 234 925 1515 107 912 1095 1742 808 349 1459 22 70 387 896 1800 931 313 1235 1383 481 1499 243 33 1485 1758 29 148 394